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Ruxolitinib for the treatment of steroid | 合法藥品大搜索

Ruxolitinib for the treatment of steroid

由MJagasia著作·2020·被引用66次—Ruxolitinibproduceddurableresponsesandencouragingsurvivalcomparedwithhistoricaldatainpatientswithsteroid-refractoryaGVHDwho ...

 Ruxolitinib for the treatment of steroid

Ruxolitinib in corticosteroid-refractory graft-versus-host disease after allogeneic stem cell transplantation: a multicenter survey. [1]

Zeiser R, Burchert A, Lengerke C, Verbeek M, Maas-Bauer K, Metzelder SK, Spoerl S, Ditschkowski M, Ecsedi M, Sockel K, Ayuk F, Ajib S, de Fontbrune FS, Na IK, Penter L, Holtick U, Wolf D, Schuler E, Meyer E, Apostolova P, Bertz H, Marks R, Lübbert M, Wäsch R, Scheid C, Stölzel F, Ordemann R, Bug G, Kobbe G, Negrin R, Brune M, Spyridonidis A, Schmitt-Gräff A, van der Velden W, Huls G, Mielke S, Grigoleit GU, Kuball J, Flynn R, Ihorst G, Du J, Blazar BR, Arnold R, Kröger N, Passweg J, Halter J, Socié G, Beelen D, Peschel C, Neubauer A, Finke J, Duyster J, von Bubnoff N. Zeiser R, et al. Leukemia. 2015 Oct;29(10):2062-8. doi: 10.1038/leu.2015.212. Epub 2015 Jul 31. Leukemia. 2015. PMID: 26228813 Free PMC article.

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Ruxolitinib for Glucocorticoid | 合法藥品大搜索
由 R Zeiser 著作 · 2020 · 被引用 123 次 — Ruxolitinib is an oral selective inhibitor of JAK1 and JAK2 that reduces the incidence and severity of GVHD in vivo while preserving graft- ... Read More
Ruxolitinib for steroid-resistant acute GVHD | 合法藥品大搜索
2020年5月14日 — Jagasia et al convincingly demonstrate that ruxolitinib may rescue approximately half of patients with steroid-refractory acute GVHD: 1-year NRM ... Read More
Ruxolitinib for Glucocorticoid | 合法藥品大搜索
由 R Zeiser 著作 · 2020 · 被引用 123 次 — Background: Acute graft-versus-host disease (GVHD) remains a major limitation of allogeneic stem-cell transplantation; not all patients have a ... Read More
Ruxolitinib for the treatment of steroid | 合法藥品大搜索
由 M Jagasia 著作 · 2020 · 被引用 66 次 — Ruxolitinib produced durable responses and encouraging survival compared with historical data in patients with steroid-refractory aGVHD who ... Read More
Ruxolitinib as Salvage Therapy for Chronic Graft | 合法藥品大搜索
由 B Modi 著作 · 2019 · 被引用 37 次 — Ruxolitinib, a selective JAK1/2 inhibitor, has recently gained favor as a second-line approach in patients with steroid-refractory cGVHD. ... Furthermore, we ... Read More
Evaluation of Ruxolitinib for Steroid | 合法藥品大搜索
由 H Wu 著作 · 2021 · 被引用 3 次 — Thereafter, the Ruxolitinib for the Treatment of Steroid-Refractory Acute GVHD (REACH-1) study investigated ruxolitinib in treating SR-aGVHD and ... Read More
Ruxolitinib Benefits Some Patients with Graft | 合法藥品大搜索
2020年5月29日 — Ruxolitinib, a targeted therapy that patients take as a pill, inhibits two proteins, JAK1 and JAK2, that are thought to play a role in GVHD. Read More
FDA Grants Ruxolitinib Priority Review to Treat Chronic GVHD | 合法藥品大搜索
2021年2月23日 — In the overall trial, 48% of patients had moderate chronic GVHD and 52% had severe chronic GVHD. As of May 8, 2020, 50% of the patients had ... Read More
Ruxolitinib in refractory acute and chronic graft | 合法藥品大搜索
由 VE Gómez 著作 · 2020 · 被引用 24 次 — In summary, ruxolitinib in the real life setting has been shown as an effective and safe treatment option for GVHD patients, with an ORR of 69.5 ... Read More
Coronavirus » Ruxolitinib for chronic and acute graft versus ... | 合法藥品大搜索
2020年11月11日 — These documents set out the recommendations for the use of ruxolitinib in graft versus host disease (GvHD) in the context of COVID-19. Read More
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