Mechanism of action of nalidixic acid | 合法藥品大搜索

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Nalidixic acid and related antibiotics inhibit a subunit of DNA gyrase and topoisomerase IV and induce formation of cleavage complexes. ... It also inhibits the ... Read More

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由 N Bouck 著作 · 1970 · 被引用 42 次 — When nalidixic acid, a specific and effective inhibitor of cellular deoxyribonucleic acid synthesis, is added to conjugating bacteria at any time during mating, it stops ... Read More

由 WA Goss 著作 · 1965 · 被引用 390 次 — coli 15TAU to synthesize DNA in a medium containing thymine, arginine, and uracil may be restored by a simple filtration and washing process, indicating that the ... Read More

由 WH Deitz 著作 · 1966 · 被引用 195 次 — 1966.—Nalidixic acid selectively inhibited deoxyribonucleic acid (DNA) synthesis in cultures of Escherichia coli 15TAU. Protein and ribonucleic acid synthesis ... Read More

由 A Sugino 著作 · 1977 · 被引用 935 次 — Nalidixic and oxolinic acids inhibit DNA gyrase activity and induce formation of a relaxation complex analogue. Treatment of the complex with sodium dodecyl ... Read More

由 GJ Bourguignon 著作 · 1973 · 被引用 129 次 — With three independent techniques (absorption spectrophotometry, measurement of the deoxyribonucleic acid [DNA] melting temperature, and equilibrium ... Read More

由 N Bouck 著作 · 1970 · 被引用 42 次 — When nalidixic acid, a specific and effective inhibitor of cellular deoxyribonucleic acid synthesis, is added to conjugating bacteria at any time during mating, ... Read More