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Lacosamide mechanism | 合法藥品大搜索

Lacosamide mechanism

,由MARogawski著作·2015·被引用124次—Currently,lacosamideistheonlyknownantiepilepticdruginclinicalpracticethatexertsitsanticonvulsantactivitypredominantlybyselectivelyenhancingslow ...,由ACErrington著作·2006·被引用145次—Lacosamide(LCM)isanticonvulsantinanimalmodelsandisinphase3assessmentforepilepsyandneuropathicpain.Hereweseektoidentifycellularactions ...,由CKellinghaus著作·2009·被引用75次—Lacosamide(LCM)isanovelagentthathasbeendevelopedasanantiepilepticdrug.InvitrostudiessuggestthatLCMmodulat...

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Lacosamide | 合法藥品大搜索
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Current understanding of the mechanism of action ... | 合法藥品大搜索
由 MA Rogawski 著作 · 2015 · 被引用 124 次 — Currently, lacosamide is the only known antiepileptic drug in clinical practice that exerts its anticonvulsant activity predominantly by selectively enhancing slow ... Read More
Seeking a mechanism of action for the novel anticonvulsant ... | 合法藥品大搜索
由 AC Errington 著作 · 2006 · 被引用 145 次 — Lacosamide (LCM) is anticonvulsant in animal models and is in phase 3 assessment for epilepsy and neuropathic pain. Here we seek to identify cellular actions ... Read More
Lacosamide as treatment for partial epilepsy | 合法藥品大搜索
由 C Kellinghaus 著作 · 2009 · 被引用 75 次 — Lacosamide (LCM) is a novel agent that has been developed as an antiepileptic drug. In vitro studies suggest that LCM modulates ... Read More
Lacosamide | 合法藥品大搜索
由 G Curia 著作 · 2009 · 被引用 83 次 — The mechanism of action of several antiepileptic drugs (AEDs) rests on their ... In contrast, lacosamide facilitates slow inactivation of sodium channels both in ... Read More
Lacosamide | 合法藥品大搜索
Lacosamide has a dual mechanism of action. It also modulates collapsin response mediator protein 2 (CRMP-2), preventing the formation of abnormal neuronal ... Read More
Current understanding of the mechanism of action of the ... | 合法藥品大搜索
由 MA Rogawski 著作 · 2015 · 被引用 124 次 — Currently, lacosamide is the only known antiepileptic drug in clinical practice that exerts its anticonvulsant activity predominantly by selectively enhancing slow ... Read More
Lacosamide: Uses | 合法藥品大搜索
Lacosamide binds to collapsin response mediator protein-2 (CRMP-2), a phosphoprotein which is expressed primarily in the nervous system and is involved in ... Read More
Lacosamide | 合法藥品大搜索
Studies suggest that lacosamide selectively enhances slow inactivation of voltage-gated sodium channels and possibly interacts with collapsin response mediator ... Read More
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