Sunitinib mechanism | 合法藥品大搜索

,由TGuo著作·2009·被引用88次—SunitinibresistanceinGISTsharessimilarpathogeneticmechanismsidentifiedinimatinibfailure,withacquisitionofsecondarymutationsin ...,由WLWang著作·2011·被引用78次—Mechanismsofresistancetoimatinibandsunitinibingastrointestinalstromaltumor.CancerChemotherPharmacol.2011Jan;67Suppl1:S15-24.doi: ...,由KJGotink著作·2011·被引用266次—Weanalyzedtumorsunitiniblevelsinmiceandpatientsandstudiedsensitivityandresistancemechanismstosunitinib.Experimentaldesign: ...,由CLeTourneau著作...

Understanding the molecular | 合法藥品大搜索

Mechanisms of sunitinib resistance in gastrointestinal stromal ... | 合法藥品大搜索

由 T Guo 著作 · 2009 · 被引用 88 次 — Sunitinib resistance in GIST shares similar pathogenetic mechanisms identified in imatinib failure, with acquisition of secondary mutations in ... Read More

Mechanisms of resistance to imatinib and sunitinib in ... | 合法藥品大搜索

由 WL Wang 著作 · 2011 · 被引用 78 次 — Mechanisms of resistance to imatinib and sunitinib in gastrointestinal stromal tumor. Cancer Chemother Pharmacol. 2011 Jan;67 Suppl 1:S15-24. doi: ... Read More

Lysosomal sequestration of sunitinib | 合法藥品大搜索

由 KJ Gotink 著作 · 2011 · 被引用 266 次 — We analyzed tumor sunitinib levels in mice and patients and studied sensitivity and resistance mechanisms to sunitinib. Experimental design: ... Read More

Sunitinib | 合法藥品大搜索

由 C Le Tourneau 著作 · 2007 · 被引用 182 次 — In vitro, sunitinib inhibited the growth of cell lines driven by VEGF, SCF, and PDGF and induced apoptosis of human umbilical vein endothelial cells (Mendel et al ... Read More

Sunitinib: the antiangiogenic effects and beyond | 合法藥品大搜索

Mechanism of action · 由 Z Hao 著作 · 2016 · 被引用 46 次 — Sunitinib has also been implicated in enhancing cancer invasiveness and metastasis. Mechanisms of resistance are poorly ... Read More

Sunitinib | 合法藥品大搜索

Mechanism of action — Mechanism of action[edit]. Sunitinib inhibits cellular signaling by targeting multiple receptor tyrosine kinases (RTKs). These ... Read More

Sunitinib: Uses, Interactions | 合法藥品大搜索

Sunitinib inhibits cellular signaling by targeting multiple RTKs. These include all platelet-derived growth factor receptors (PDGF-R) and vascular endothelial growth ... Read More

Sunitinib | 合法藥品大搜索

由 Z Hao 著作 · 2016 · 被引用 46 次 — Mechanistically, sunitinib inhibits multiple receptor tyrosine kinases, especially those involved in angiogenesis, that is, vascular endothelial ... Read More

New Insights into Molecular Mechanisms of Sunitinib ... | 合法藥品大搜索

由 G Aparicio-Gallego 著作 · 2011 · 被引用 110 次 — Sunitinib induces an increase in the production of amylase and/or lipase by the exocrine pancreas (4, 8), probably in response to necrosis or ... Read More

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