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Levetiracetam vs. brivaracetam for adults with ... | 合法藥品大搜索

Levetiracetam vs. brivaracetam for adults with ...

由LZhang著作·2016·被引用24次—Purpose:Thestudyaimedtocomparetheefficacyandtolerabilityoflevetiracetam(LEV)andbrivaracetam(BRV)inadultswithrefractoryfocalseizures.Method: ...

 Levetiracetam vs. brivaracetam for adults with ...

Purpose: The study aimed to compare the efficacy and tolerability of levetiracetam (LEV) and brivaracetam (BRV) in adults with refractory focal seizures.

Method: We systematically queried Medline, Embase, and the Cochrane Library. We looked for additional studies in the references of all identified publications and ClinicalTrials.gov. The cutoff day was November 6, 2015. Randomized, double-blind, placebo-controlled trials were included. The indirect comparison for 50% responder rate, seizure-free rate, and adverse effects were conducted.

Results: Thirteen trials enrolling 1765 patients in the LEV group and 1919 patients in the BRV group were included. No statistically signifi...

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長庚藥學學報2018 年4月_完稿 | 合法藥品大搜索
2018年4月30日 — 來減少對快速刺激的反應，遂而產生抗癲癇作. 針對SV2A 受器親和力，brivaracetam levetiracetam 更高，結合力高出15. 於2016 年先後於歐洲 ... Read More
Levetiracetam and brivaracetam | 合法藥品大搜索
由 BJ Steinhoff 著作 · 2019 · 被引用 17 次 — Levetiracetam (LEV) and brivaracetam (BRV) are pyrrolidone derivate compounds binding at the presynaptic SV2A receptor site and are thus ... Read More
Brivaracetam versus Levetiracetam for Epilepsy | 合法藥品大搜索
由 A Subramonian 著作 · 2020 — Brivaracetam (BRV) is an AED in the racetam group which was discovered as an analog to the related racetam drug levetiracetam (LEV). Both ... Read More
Levetiracetam and brivaracetam: a review of ... | 合法藥品大搜索
由 BJ Steinhoff 著作 · 2019 · 被引用 17 次 — Levetiracetam (LEV) and brivaracetam (BRV) are pyrrolidone derivate compounds binding at the presynaptic SV2A receptor site and are thus ... Read More
Levetiracetam vs. brivaracetam for adults with refractory focal ... | 合法藥品大搜索
由 L Zhang 著作 · 2016 · 被引用 24 次 — Brivaracetam (BRV) is a highly selective and reversible SV2A ligand with a 15- to 30-fold higher affinity than levetiracetam has in the rat or human brain [3]. Read More
Levetiracetam and brivaracetam | 合法藥品大搜索
由 BJ Steinhoff 著作 · 2019 · 被引用 17 次 — Levetiracetam and brivaracetam: a review of evidence from clinical trials and clinical experience. Ther Adv Neurol Disord. 2019 Sep 9;12:1756286419873518. Read More
Brivaracetam in the treatment of focal and idiopathic ... | 合法藥品大搜索
由 A Strzelczyk 著作 · 2016 · 被引用 43 次 — Brivaracetam is the latest approved antiepileptic drug in focal epilepsy and exhibits ... Immediate switch from levetiracetam to brivaracetam at a conversion ratio ... Read More
Levetiracetam vs. brivaracetam for adults with ... | 合法藥品大搜索
由 L Zhang 著作 · 2016 · 被引用 24 次 — Purpose: The study aimed to compare the efficacy and tolerability of levetiracetam (LEV) and brivaracetam (BRV) in adults with refractory focal seizures. Method: ... Read More
Brivaracetam is superior to levetiracetam in a rat model of post ... | 合法藥品大搜索
由 KK Tai 著作 · 2007 · 被引用 43 次 — In the present study, we evaluated the anti-seizure and anti-myoclonic activity of levetiracetam and brivaracetam in an established rat model of cardiac ... Read More
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