Brivaracetam is superior to levetiracetam in a rat model of post ... | 合法藥品大搜索

2018年4月30日 — 來減少對快速刺激的反應，遂而產生抗癲癇作. 針對SV2A 受器親和力，brivaracetam levetiracetam 更高，結合力高出15. 於2016 年先後於歐洲 ... Read More

由 BJ Steinhoff 著作 · 2019 · 被引用 17 次 — Levetiracetam (LEV) and brivaracetam (BRV) are pyrrolidone derivate compounds binding at the presynaptic SV2A receptor site and are thus ... Read More

由 A Subramonian 著作 · 2020 — Brivaracetam (BRV) is an AED in the racetam group which was discovered as an analog to the related racetam drug levetiracetam (LEV). Both ... Read More

由 BJ Steinhoff 著作 · 2019 · 被引用 17 次 — Levetiracetam (LEV) and brivaracetam (BRV) are pyrrolidone derivate compounds binding at the presynaptic SV2A receptor site and are thus ... Read More

由 L Zhang 著作 · 2016 · 被引用 24 次 — Brivaracetam (BRV) is a highly selective and reversible SV2A ligand with a 15- to 30-fold higher affinity than levetiracetam has in the rat or human brain [3]. Read More

由 BJ Steinhoff 著作 · 2019 · 被引用 17 次 — Levetiracetam and brivaracetam: a review of evidence from clinical trials and clinical experience. Ther Adv Neurol Disord. 2019 Sep 9;12:1756286419873518. Read More

由 A Strzelczyk 著作 · 2016 · 被引用 43 次 — Brivaracetam is the latest approved antiepileptic drug in focal epilepsy and exhibits ... Immediate switch from levetiracetam to brivaracetam at a conversion ratio ... Read More

由 L Zhang 著作 · 2016 · 被引用 24 次 — Purpose: The study aimed to compare the efficacy and tolerability of levetiracetam (LEV) and brivaracetam (BRV) in adults with refractory focal seizures. Method: ... Read More

由 KK Tai 著作 · 2007 · 被引用 43 次 — In the present study, we evaluated the anti-seizure and anti-myoclonic activity of levetiracetam and brivaracetam in an established rat model of cardiac ... Read More