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Danazol as first | 合法藥品大搜索

Danazol as first

由JCJaime-Pérez著作·2011·被引用65次—Nopatienttreatedwithdanazolsufferedclonalevolutionofhis/herdisease.AlthoughATGplusCsAisthetherapyofchoiceforAApatients ...

 Danazol as first

Immunosuppressive therapy (IST) with anti-thymocyte globulin (ATG) plus cyclosporine A (CsA) is the standard treatment for aplastic anemia (AA) patients not eligible for allogeneic hematopoietic stem cell transplantation (HSCT). In the absence of ATG + CsA, androgens continue to be a treatment option. We documented the clinical evolution of AA patients treated with danazol instead of ATG + CsA. AA patients lacking both, human leukocyte antigen-matched donor and access to IST, were treated with danazol and modern support therapy and compared with those receiving a HSCT. Overall survival (OS), response rates, and death risk odds were calculated. Fifty AA patients were studied. Thirteen received a HSCT and 37 danazol and support therapy. Median daily dose of danazol was 400 mg (300 to 600 mg), administered during a median of 12 months. Five-year OS was higher for patients receiving HSCT (92%) compared to the danazol gr...

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Danazol as first | 合法藥品大搜索
由 JC Jaime-Pérez 著作 · 2011 · 被引用 65 次 — No patient treated with danazol suffered clonal evolution of his/her disease. Although ATG plus CsA is the therapy of choice for AA patients ... Read More
Danazol increases T regulatory cells in patients with ... | 合法藥品大搜索
由 H Khurana 著作 · 2018 · 被引用 4 次 — Objectives: Danazol is an attenuated androgen and is used in the treatment of aplastic anemia (AA) in resource constraint settings. We chose to study the role of​ ... Read More
Danazol therapy for aplastic anemia refractory to ... | 合法藥品大搜索
由 T Chuhjo 著作 · 2008 · 被引用 39 次 — Sixteen patients (12 males and four females; six severe cases and 10 moderate cases) were treated with 300 mg of danazol daily for 12 weeks. All patients ... Read More
[Severe aplastic anemia remarkably improved by a treatment ... | 合法藥品大搜索
由 K Miyamura 著作 · 1989 — Treatment schedule were 1) m-PSL 1,000 mg (day 1-4), 500 mg (5-8)--then tapered. 2) ALG lg/day (day 4-8) 3) danazol 600 mg/day. During ALG administration, ... Read More
Danazol increases T regulatory cells in patients with aplastic ... | 合法藥品大搜索
由 H Khurana 著作 · 2018 · 被引用 4 次 — Objectives: Danazol is an attenuated androgen and is used in the treatment of aplastic anemia (AA) in resource constraint settings. We chose to ... Read More
Danazol for Genetic Bone Marrow and Lung Disorders | 合法藥品大搜索
Currently, doctors use a male hormone-based drug called Danazol to improve bone marrow function and treat aplastic anemia. More information is needed on ... Read More
Nontransplant therapy for bone marrow failure | 合法藥品大搜索
2016年12月2日 — Danazol, which is traditionally less preferred for treating cytopenias, ... During the last 3 decades, patients with aplastic anemia (AA) have ... Read More
Danazol therapy for aplastic anemia refractory to ... | 合法藥品大搜索
由 T Chuhjo 著作 · 2008 · 被引用 39 次 — Although there are anecdotal reports of the efficacy of danazol in the treatment of aplastic anemia (AA), there has been no systematic study to ... Read More
(PDF) Danazol as first | 合法藥品大搜索
The beneficial effect of danazol has also been shown in treating aplastic anemia and myelodysplastic syndromes (MDS), characterized by ineffective ... Read More
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