Hydralazine | 合法藥品大搜索

Hydralazinebelongstothehydrazinophthalazineclassofdrugs.History[edit].Theantihypertensiveactivityofhydralazinewasdiscoveredbyscientistsat ...

Anti-hypertension medication

Hydralazine, sold under the brand name Apresoline among others, is a medication used to treat high blood pressure and heart failure.[2] This includes high blood pressure in pregnancy and very high blood pressure resulting in symptoms.[3] It has been found to be particularly useful in heart failure, together with isosorbide dinitrate, for treatment of people of African descent.[2] It is given by mouth or by injection into a vein.[3] Effects usually begin around 15 minutes and last up to six hours.[2]

Common side effects include headache and fast heart rate.[2] It is not recommended in people with coronary artery disease or in those with rheumatic heart disease that affects the mitral valve.[2] In those with kidney disease a low dose is recommended.[3] Hydralazine is in the vasodilator family of medications, so it is believed to work by causing the dilation of blood vessels.[2]

Hydralazine was discovered while scientists at Ciba were l...