Apresoline (hydralazine hydrochloride) for Hypertension (High ... | 合法藥品大搜索

ApresolinebelongstoaclassofdrugscalledVasodilators.WhatAreSideEffectsofApresoline?SideeffectsofApresolineinclude:chestpainorpressure ...

In a few patients hydralazine may produce a clinical picture simulating systemic lupus erythematosus including glomerulonephritis. In such patients hydralazine should be discontinued unless the benefit-to-risk determination requires continued antihypertensive therapy with this drug. Symptoms and signs usually regress when the drug is discontinued but residua have been detected many years later. Long-term treatment with steroids may be necessary. (See PRECAUTIONS, Laboratory Tests.)

General

Myocardial stimulation produced by Apresoline (hydralazine) can cause anginal attacks and ECG[1] changes of myocardial ischemia[2]. The drug has been implicated in the production of myocardial infarction[3]. It must, therefore, be used with caution in patients with suspected coronary artery disease.

The “hyperdynamic" circulation[4] caused by Apresoline (hydralazin...