Integrins | 合法藥品大搜索

整合素（英語：Integrin，又譯為整聯蛋白）是一種介導細胞和其外環境（如細胞外基質，Extra Cellular Matrix）之間的連接的跨膜受體，普遍存在於脊椎動物的 ... Read More

Integrins are transmembrane receptors that facilitate cell-cell and cell-​extracellular matrix (ECM) adhesion. Upon ligand binding, integrins activate signal ... Read More

Integrins are proteins that function mechanically, by attaching the cell cytoskeleton to the extracellular matrix (ECM), and biochemically, by sensing whether ... Read More

Integrin activation is an important mechanism through which cells regulate integrin function by manipulating the ligand affinity of integrins spatially and temporally. Read More

由 B Alberts 著作 · 2002 · 被引用 169 次 — Integrins are the principal receptors used by animal cells to bind to the extracellular matrix. They are heterodimers and function as transmembrane linkers between ... Read More

由 M Barczyk 著作 · 2010 · 被引用 1528 次 — Integrins are cell adhesion receptors that are evolutionary old and that play important roles during developmental and pathological processes. Read More

由 EHJ Danen 著作 · 2013 · 被引用 26 次 — Integrins are heterodimeric transmembrane receptors that mediate cell-adhesion.​1 With their extracellular head region, most integrins bind extracellular matrix ... Read More

Interactions between integrins and the extracellular matrix mediate intracellular signaling mechanisms to regulate cell survival, differentiation, cell cycle ... Read More

Integrin allostery lends itself to the development of integrin-targeted drugs that can regulate conformational changes and thus ligand binding, not just as ... Read More